The incident was reported at around 11.41am at Bonemill Junction, near the A17/A153 roundabout close to the Agra restaurant.
The A17 was said to be completely closed at this location and drivers were asked to avoid the area.
By 1.30pm The vehicles involved had been removed and the A17 was reopened.
No-one was reported to have been seriously hurt.
Later, at around 2.30pm, emergency services were called to the scene of another collision, this time on the A15 at Haconby, close to the A15/West Road junction, which is the turn-off for Billingborough.
Three vehicles were involved but no-one was said to have been hurt.
Officers worked to get the road reopened as quickly as possible and traffic was freed up by 6pm.