Harworth maintain perfect start
A bright start by the hosts saw them score twice in the first five minutes through Sides and Belshaw.
Edmundson extended the lead shortly after the hour-mark but then Harworth took their foot off the pedal and let the visitors back into the game.
Aaron Darcy and James Whitmore scored in quick succession to make it 3-2, and the momentum was with Sherwood to complete the comeback.
But Harworth dug deep and two late goals from Anderson and Belshaw took the game away from Sherwood.
Harworth, who beat Bentley Colliery 3-0 on Saturday in their first home game of the new campaign, have taken nine points from their first three games.
Harworth travel to Yorkshire Main at the weekend before entertaining Thorne Colliery at home on Bank Holiday Monday.